Apocrine glands are located primarily in the underarm, groin, and breast areas. Eccrine and apocrine naevi are rare malformations of the glandular component of an eccrine or apocrine gland. 1-3 With single or multimodal therapies, including surgery, chemotherapy and radiation, the median survival time is one to two years.

4-6 Toceranib phosphate, which is FDA-approved for the treatment of high-grade cutaneous mast cell … Viral Infections . Apocrine gland anal sac adenocarcinomas (AGASACAs) are locally invasive and, in 50% to 90% of canine cases, have metastasized by the time of diagnosis. A mass of pubic hair can trap heat in the skin and cause apocrine glands to secrete excess sweat. Sweat gland naevus. Apocrine glands. Hidradenitis occurs when the hair follicles and nearby apocrine glands (sweat glands) on the underarms, groin, buttocks and under the breasts become infected and inflamed. Due to bacterial infection around apocrine glands of axilla, occasionally perineum or vulva Usually due to anaerobes, which cause an offensive smell Staphylococcus aureus, Strep Viridans and E. coli are also involved Associated with cigarette smoking (Dermatology 1999;198:261) and obesity Clinical features . No value can be attached to the odor, or for that matter to the function of the glands themselves, which indeed have been entirely supplanted by the exocrine sweat glands.

Malignant ( cancerous ) tumors can grow quickly and cause loss of movement in the affected side of the face. Get a printable copy (PDF file) of the complete article (437K), or click on a page image below to browse page by page. Chronic bouts of hidradenitis suppurativa can form networks of scars just below the skin's … One of the most advanced and uncomfortable forms of apocrine gland infection is hidradenitis suppurativa, also known as acne inversa. The coiled gland consists of one layer of secretory cells around a lumen that is about ten times the diameter of its eccrine counterpart. The condition appears as blackheads and painful, sometimes pustulent bumps in the groin and armpits. While what actually causes hidradenitis is poorly understood, the process itself is clearly documented. It can persist for years, and often gets worse as the victim ages. A salivary gland infection caused by a benign tumor may cause an enlargement of the glands. If not treated, salivary gland infections can cause severe pain, high fevers and abscess (pus collection). Although the apocrine gland is not a scent gland in the usual sense, its sweat becomes odorous by the decomposing action of resident skin bacteria, and only by gram-positive ones at that. In contrast, apocrine glands produce an oily fluid rich in triglycerides and fatty acids – subsequent colonisation by anaerobic bacteria results in body odour. Apocrine glands are composed of three components: (1) the intraepithelial duct, (2) the intradermal duct, and (3) a coiled gland in the deep dermis or at the junction of the dermis and subcutaneous fat, which contains the secretory portion.

Viral infections such as mumps, flu and others can cause swelling of the salivary glands. What is hidradenitis?

Swelling occurs in parotid glands on both sides of the face, giving the appearance of "chipmunk cheeks." Sweat from the apocrine glands tends to be thicker than that produced by the eccrine glands. Full text Full text is available as a scanned copy of the original print version.