The first, and possibly the most overlooked, sign of stress is the hedgehog’s frantic attempt to get away.
Other signs of a sick hedgehog include lethargy, panting or labored breathing, a dull expression, discharge from the nose or eyes, sneezing, coughing and paralysis. It should not be dry, bubbly, or running. Signs of stress. Many hedgehogs are busy and want to try to explore but a stressed hedgehog will be much more persistent and not easily distracted.

Weight loss, loose or reduced stools and reduced or bloody urine also can indicate your hedgehog is under the weather. The stressed hedgehog may also twitch or shake its head nervously. The hedgehog’s nose should be moist and clean. Signs and Symptoms of Wobbly Hedgehog Syndrome A first sign of wobbly hedgehog syndrome is usually the inability to ball up completely.
Check its eyes to make sure they are bold, clear, round, and bright.

The eyes should be wide open. The first, and possibly the most overlooked, sign of stress is the hedgehog’s frantic attempt to get away. Progressively myelin in their brain decreases, causing slow progression of the intermittent inability to balance and coordinate movements. The hedgehog … The stressed hedgehog may also twitch or shake its head nervously.